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  • It was discovered that naltrexone and bupropion combined, that could be marketed down the road as Contrave, have better weight loss results than diet and exercise alone.

    Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people that go through it you need to err along the side of caution and let the FDA do its job and demand some investigation be done so that the public understands the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on the medications.

    Researchers found that participants investing in this drug for any year, lost weight within four weeks and have kept the extra weight off during the entire 56 weeks with the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which are made up of many active ingredient, which might make them more effective and safer.

    Combo-pilling could be the newest fad or even better the newest to come under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular will be the fact that by right now there are no long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA.

    Seizures certainly are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug could also raise blood pressure level and heartrate, and must not be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.

    Most of the combinations which are used to enhance weight reduction involve an amphetamine plus an antidepressant. Phentermine and Prozac are a popular combination which were around for a long time, and although it has been around nobody wants to truly combine both the and try to get FDA approval to advertise it as a fat loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies do not want to be involved in combining medications and selling them something have to be wrong with the combination. In fairness there is certainly one weight loss combination pill that is certainly in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and substance abuse, while using antidepressant bupropion (Wellbutrin, Zyban) it is often given the try to move forward by an FDA advisory committee, but since yet will not be approved.

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